Microfluidics

Cell Sorting and Separation in Microfluidic Devices

Cell sorting and separation using microfluidic devices are becoming indispensable tools in biomedical research, diagnostics, and therapeutic applications. These systems leverage the unique physical properties of cells, such as size, shape, and surface markers, to efficiently sort and separate cells in a continuous flow of fluid through microchannels.Microfluidic devices use various techniques for cell sorting, including dielectrophoresis, acoustic waves, and microvalve-based systems. These methods enable high-throughput, precise separation of rare cell populations, such as stem cells, cancer cells, or immune cells, which are critical for applications like diagnostics, immunotherapy, and personalized medicine.One of the key advantages of microfluidic cell sorting is the ability to process small sample volumes with high efficiency, reducing costs and preserving cell viability. The ability to isolate individual cells also facilitates single-cell analysis, providing valuable insights into cell-specific behavior, gene expression, and drug responses.With advances in microfluidic technology, cell sorting and separation techniques continue to improve, offering more scalable, reproducible, and efficient solutions for a wide range of applications in both research and clinical settings.